15.12.2023 (09:30-19:00 CET)
Basel, Switzerland
Biozentrum, Maurice E. Müller Saal,
Spitalstrasse 41, 4056 Basel
09:30 Welcome Coffee
10:00 Welcome by Ludwig Kappos and Cristina Granziera
10:10 – 10:40 Opening lecture: Learning from other areas of medicine
Time | Title | Speaker |
10:10 – 10:40 | The patient’s digital twin | Tobias Heimann, Head of Artificial Intelligence Germany, Siemens Healthineers |
10:40 – 12:00 Session 1: Neuroimmunological mechanisms in MS
Chairs: Renaud Du Pasquier (Lausanne, CH) and Reinhard Hohlfeld (Munich, DE)
Time | Title | Speaker |
10:40 – 11:00 | Innovative concepts in neuroimmunology | Amit Bar-Or, Philadelphia, PA, USA |
11:00 – 11:15 | The B-cell perspective of MS | Tobias Derfuss, Basel, CH |
11:15 – 11:30 | A role for IgA-producing cells in MS? | Anne-Katrin Pröbstel, Basel, CH |
11:30 – 12:00 | The success story of B-cell directed therapy and new therapeutic targets | Stephen Hauser, San Francisco, CA, USA |
12:00 – 13:00 Lunch break & poster session
13:00 – 14:30 Session 2: Fluid and imaging biomarkers in MS
Chairs: Tanuja Chitnis (Boston, US) and Frederik Piehl (Stockholm, SE)
Time | Title | Speaker |
13:00 – 13:30 | What can be said at all can be clearly quantified, and whereof one cannot quantify thereof one must be silent... | Daniel S. Reich, Bethesda, MD, USA |
13:30 – 13:50 | Body fluid biomarkers in MS – finally on target? | Jens Kuhle, Basel, CH |
13:50 – 14:00 | The role of complement in MS | Johanna Oechtering, Basel, CH |
14:00 – 14:20 | Imaging axonal damage and repair in MS: the INsIDER experience | Cristina Granziera, Basel, CH |
14:20 – 14:30 | Mechanisms of clinical worsening independent of inflammatory activity in MS: an advanced MRI perspective | Alessandro Cagol, Basel, CH |
14:30 – 15:00 Coffee break & poster session
15:00 – 16:30 Session 3: Clinical trials, disease monitoring, cohort studies and pragmatic clinical trials in MS
Chairs: Maria Pia Sormani (Genova, IT) and Urs Fischer (Basel, CH)
Time | Title | Speaker |
15:00 – 15:30 | Meta-epidemiology of clinical trials | John P.A. Ioannidis, Stanford, CA, USA |
15:30 – 15:40 | The Swiss Multiple Sclerosis Cohort: a 10-year investment in quality | Giulio Disanto, Lugano, CH Jens Kuhle, Basel, CH |
15:40 – 15:50 | Neurostatus eEDSS | Marcus D’Souza, Basel, CH |
15:50 – 16:10 | Digital Biomarkers for pwMS - the dreaMS project | Johannes Lorscheider, Tim Woelfle, Basel, CH |
16:10 – 16:30 | Pragmatic trials in MS: a novel journey | Lars Hemkens, Basel, CH |
16:30 – 17:00 Coffee break & poster session
17:00 – 18:00 Session 4: Towards digital twins in neuroimmunology?
Chairs: Torsten Schwede (Basel, CH) and Jan Hillert (Stockholm, SE)
Time | Title | Speaker |
17:00 – 17:15 | The Big MS data network | Jan Hillert, Stockholm, SE |
17:15 – 17:30 | Big (great) data in immunobiology: is more always better? | Manfred Claassen, Tübingen, DE |
17:30 – 17:45 | Federated Learning as an alternative to data transfer? | Björn Tackenberg, Hoffmann La Roche, Basel, CH |
17:45 – 18:00 | Big (great) data from clinical trials: what can we learn | Amit Khanna, Novartis, Basel, CH |
18:00 Closing remarks – RC2NB 4.0: Τα πάντα ρει, μηδέποτε κατά τ‘αυτό μένειν, Ludwig Kappos (Basel, CH)
18:15 Apero Riche